http://staygifted.com/2009/07/15/5/ Questioning and Understanding MPB with Todays Treatments and Cures Sun, 20 May 2012 13:33:01 +0000 http://wordpress.org/?v=2.2.1 http://staygifted.com/2009/07/15/5/#comment-21 admin Thu, 04 Nov 2010 12:41:26 +0000 http://staygifted.com/2009/07/15/5/#comment-21 Apparently it was not new hair follicles but existing that went in to anagen: "Smaller wounds could selectively upregulate factors which are sufficient for inducing cycling of pre-existing hair follicle stem cells but not for triggering follicular neogenesis [14, 23]. The latter may result only after the skin sustains large defects. Wound size-dependent concentration effects of key signaling molecules may also contribute to these differences" But still, if this would be the same for humans a small cut on the scalp would result in thicker hair growth (resting hairs -> anagen). And that isnt the case as far as my experience go. Apparently it was not new hair follicles but existing that went in to anagen:
“Smaller wounds could selectively upregulate factors which are sufficient for inducing cycling of pre-existing hair follicle stem cells but not for triggering follicular neogenesis [14, 23]. The latter may result only after the skin sustains large defects. Wound size-dependent concentration effects of key signaling molecules may also contribute to these differences”
But still, if this would be the same for humans a small cut on the scalp would result in thicker hair growth (resting hairs -> anagen). And that isnt the case as far as my experience go.

]]> http://staygifted.com/2009/07/15/5/#comment-20 admin Thu, 04 Nov 2010 12:40:54 +0000 http://staygifted.com/2009/07/15/5/#comment-20 There is a new published study from Stanford regarding wounding and hair growth (mice). They tried smaller wounds like cuts and small circular wounds and found that even small wounds would result in pretty impressive hair growth. In these mice that is. There are some pretty impressive pictures I think, but on the other hand I know that the same injury in humans would not result in that amount of hair growth. So it could be that the follica method isnt really working on humans at it does on mice. Here is the link to the article Small cutaneous wounds induce telogen to anagen transition of murine hair follicle stem cells : http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T87-51B1WPX-1&_user=651972&_coverDate=10%2F26%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_searchStrId=1526709889&_rerunOrigin=scholar.google&_acct=C000035298&_version=1&_urlVersion=0&_userid=651972&md5=767fe4c9712fcc6c41e087bd5c325845&searchtype=a There is a new published study from Stanford regarding wounding and hair growth (mice). They tried smaller wounds like cuts and small circular wounds and found that even small wounds would result in pretty impressive hair growth. In these mice that is. There are some pretty impressive pictures I think, but on the other hand I know that the same injury in humans would not result in that amount of hair growth. So it could be that the follica method isnt really working on humans at it does on mice.
Here is the link to the article Small cutaneous wounds induce telogen to anagen transition of murine hair follicle stem cells : http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T87-51B1WPX-1&_user=651972&_coverDate=10%2F26%2F2010&_rdoc=1&_fmt=high&_orig=search&_origin=search&_sort=d&_docanchor=&view=c&_searchStrId=1526709889&_rerunOrigin=scholar.google&_acct=C000035298&_version=1&_urlVersion=0&_userid=651972&md5=767fe4c9712fcc6c41e087bd5c325845&searchtype=a

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